Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep81 | Calcium and Bone | ECE2021

Bone consequences of high dose denosumab to treat an aneurysmal bone cyst, an example of the European Reference Network support

Sindaco Giulia Del , Berlanga Pablo , Brugieres Laurence , Thebault Eric , Mantovani Giovanna , Wicart Philippe , Agnès Linglart

Aneurysmal bone cysts (ABCs) are rare pseudotumoral bone lesions with potential aggressive behavior due to the extensive destruction of surrounding bone. Besides surgery, denosumab has been investigated as a treatment for benign fibro-osseous lesions. As for ABCs, pediatric experience is limited, reporting mainly beneficial effects on lesions growth and associated pain. Some reports included well known side effects associated with denosumab, such as the rebound hypercalcemia a...